The diagnosis of leprosy is not straightforward. It is normally based on clinical signs and symptoms, but sometimes needs laboratory and other investigations. The development of a diagnostic test to detect early leprosy before it becomes clinically apparent is an exciting new possibility for reducing transmission. Several organisations and institutions are working on number of different dimensions of development of such tests, using DNA, detecting antibodies, ultrasound imaging of nerves and cell phones to assist in diagnoses.
Evaluation of the qPCR in household contact monitoring – Fundação Oswaldo Cruz (FIOCRUZ)
Field-compatible diagnostic lateral-flow test – Leiden University Medical Center (LUMC,) Erasmus
NDO-LID® rapid lateral flow tests with a new cell phone-based test reader platform (Smart Reader®) – Infectious Disease Research Institute (IDRI)
Integration of rapid diagnostic tests to facilitate case management of leprosy – Infectious Disease Research Institute (IDRI)
Research on leprosy treatment – Faculté de Médecine Pierre et Marie Curie (FMPMC)
Basic research at Mycobacterial Research Laboratory (MRL), Anandaban Hospital, Nepal – The Leprosy Mission Nepal (TLM Nepal)
ILEP Member projects
Some ILEP Members are involved in research related to diagnostic tests, working on various research projects in search for new diagnostics.